This riff has a really nice groove with the drums. As far as your picking, it will pretty much stay the same throughout this section. When you look at the tab, you'll see that most of the notes are in groupings of 2. For each grouping, you'll simply do a downstroke followed by an upstroke.
When we get to bar 27, we'll basically be playing the same thing we played in previous bars, except now we'll be playing a solid quarter note on the 4th beat of each measure. Be sure to give that quarter note a good amount of vibrato as well.
When you're ready, head on over to the backing track!